This is the NanoDefiner e-tool, a decision support framework for the characterisation of potential nanomaterials. It is one of the products delivered by the NanoDefine project.
The NanoDefine project has received funding from the European Union’s Seventh Programme for research, technological development and demonstration under grant agreement No 604347.
This version displays the official and limited access version of the NanoDefiner e-tool. When testing and reporting issues or providing feedback, please always include the following version information:
Please make sure to delete NanoDefiner cookies after every update.
The e-tool is tested with recent versions of Mozilla Firefox, Google Chrome / Chromium, and Safari. If you are using a different browser and experience problems, please consider using one of the aforementioned browsers.
If you want to run your own NanoDefiner installation, visit the Download page for further information
Docker provides lightweight virtualisation in the form of containers which are derived from images.
The NanoDefiner e-tool is available on DockerHub as nanodefiner/nanodefiner, but it comes without a database management system (DBMS). You either have to mount your own configuration and specify an external DBMS server, or run a separate docker container with a DBMS with docker compose as seen in the provided docker-compose.yaml .
If you want to upgrade your NanoDefiner e-tool installation or do not want to use the provided docker image, this package contains only the standalone JAR as well as installation/upgrade instructions. It only requires Java 8 and a working DBMS server.
Development team at University of Applied Sciences and Arts Dortmund:
For questions and feedback feel free to use the feedback button on the test service page, the GitHub issue tracker or write us an e-mail.
The NanoDefine Methods Manual covers the whole knowledge gained in the NanoDefine project. It has been published in three parts as JRC Technical Reports that focus on (i) the NanoDefiner framework and tools, (ii) the evaluation of methods, and (iii) standard operating procedures (SOPs).
In EU Science Hub Publications:
Mech, A., Rauscher, H., Babick, F., Hodoroaba, V.-D., Ghanem, A., Wohlleben, W., Marvin, H., Weigel, S., Brüngel, R., Friedrich, C. M. (2020). The NanoDefine Methods Manual. Part 1: The NanoDefiner Framework and Tools. EUR 29876 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-11950-0, doi:10.2760/55181, JRC117501
Mech, A., Rauscher, H., Rasmussen, K., Babick, F., Hodoroaba, V.-D., Ghanem, A., Wohlleben, W., Marvin, H., Brüngel, R., Friedrich, C. M. (2020). The NanoDefine Methods Manual. Part 2: Evaluation of methods. EUR 29876 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-11953-1, doi:10.2760/071877, JRC117501
Mech, A., Rauscher, H., Rasmussen, K., Babick, F., Hodoroaba, V.-D., Ghanem, A., Wohlleben, W., Marvin, H., Brüngel, R., Friedrich, C. M., Löschner, K., Gilliland, D. (2020). The NanoDefine Methods Manual. Part 3: Standard Operating Procedures (SOPs). EUR 29876 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-11955-5, doi:10.2760/02910, JRC117501
In addition, it is available in a compact book format that covers all three parts.
In EU Science Hub Publications:
Mech, A., Rauscher, H., Babick, F., Hodoroaba, V.-D., Ghanem, A., Wohlleben, W., Marvin, H., Weigel, S., Brüngel, R., Friedrich, C., Rasmussen, K., Loeschner, K., Gilliland, D. (2020). The NanoDefine Methods Manual. EUR 29876 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-12335-4, doi:10.2760/79490, JRC117501
The ParticleSizer is an ImageJ plug-in for Transmission Electron Microscopy (TEM) image analysis. It automatically measures distributions of characteristic size and shape properties of potential nanomaterials. Analysis results may be exported in a text-based file format and imported into the NanoDefiner for an automatic nano/non-nano/borderline decision on a specific material.
The Single Particle Calculation tool version 2 (SPCTv2) allows to generate spreadsheet-based analysis data of single particle Inductively Coupled Plasma Mass Spectrometry (spICP-MS) measurements. Data generated by the SPCTv2 can be imported into the NanoDefiner for an automatic nano/non-nano/borderline decision on a specific material.
The AutoEM-toolbox is a software for automatic acquisition and analysis of nanoparticles in the transmission electron microscope.
Mech, A., Wohlleben, W., Ghanem, A., Hodoroaba, V.‐D., Weigel, S., Babick, F., Brüngel, R., Friedrich, C. M., Rasmussen, K., Rauscher, H. (2020). Nano or Not Nano? A Structured Approach for Identifying Nanomaterials According to the European Commission's Definition. Small, 2002228. doi:10.1002/smll.202002228
Mech, A., Rauscher, H., Babick, F., Hodoroaba, V.-D., Ghanem, A., Wohlleben, W., Marvin, H., Weigel, S., Brüngel, R., Friedrich, C., Rasmussen, K., Loeschner, K., Gilliland, D. (2020). The NanoDefine Methods Manual. EUR 29876 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-12335-4, doi:10.2760/79490, JRC117501
Mech, A., Rauscher, H., Babick, F., Hodoroaba, V.-D., Ghanem, A., Wohlleben, W., Marvin, H., Weigel, S., Brüngel, R., Friedrich, C. M. (2020). The NanoDefine Methods Manual. Part 1: The NanoDefiner Framework and Tools. EUR 29876 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-11950-0, doi:10.2760/55181, JRC117501
Mech, A., Rauscher, H., Rasmussen, K., Babick, F., Hodoroaba, V.-D., Ghanem, A., Wohlleben, W., Marvin, H., Brüngel, R., Friedrich, C. M. (2020). The NanoDefine Methods Manual. Part 2: Evaluation of methods. EUR 29876 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-11953-1, doi:10.2760/071877, JRC117501
Mech, A., Rauscher, H., Rasmussen, K., Babick, F., Hodoroaba, V.-D., Ghanem, A., Wohlleben, W., Marvin, H., Brüngel, R., Friedrich, C. M., Löschner, K., Gilliland, D. (2020). The NanoDefine Methods Manual. Part 3: Standard Operating Procedures (SOPs). EUR 29876 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-11955-5, doi:10.2760/02910, JRC117501
Brüngel, R., Rückert, J., Wohlleben, W., Babick, F., Ghanem, A., Gaillard, C., Mech, A., Rauscher, H., Hodoroaba, V.-D., Weigel, S., Friedrich, C. M. (2019). NanoDefiner e-Tool: An Implemented Decision Support Framework for Nanomaterial Identification. Materials, 12(19), 3247. doi:10.3390/ma12193247
Rauscher, H., Mech, A., Gibson, N., Gilliland, D., Held, A., Kestens V., Koeber, R., Linsinger, T. P. J., Stefaniak, E. A. (2019). Identification of nanomaterials through measurements. EUR 29942 EN, Publications Office of the European Union, Luxembourg, 2019, ISBN 978-92-76-10371-4, doi:10.2760/053982, JRC118158
Rauscher, H., Roebben, Mech, A., Gibson, N., Kestens, V., Linsinger, T. P. J., Riego Sintes, J. An overview of concepts and terms used in the European Commission's definition of nanomaterial, EUR 29647 EN, Publications Office of the European Union, Luxembourg, 2019, ISBN 978-92-79-99660-3, doi:10.2760/459136, Publications Office of the European Union
Gaillard, C., Mech, A., Wohlleben, W., Babick, F., Hodoroaba, V.-D., Ghanem, A., Weigel, S., & Rauscher, H. (2019). A technique-driven materials categorisation scheme to support regulatory identification of nanomaterials. Nanoscale Advances, 1(2), 781–791. doi:10.1039/c8na00175h
Uusimaeki, T., Wagner, T., Lipinski, H.-G., & Kaegi, R. (2019). AutoEM: a software for automated acquisition and analysis of nanoparticles. Journal of Nanoparticle Research, 21(6). doi:10.1007/s11051-019-4555-9
Brüngel, R., Rückert, J., Wohlleben, W., Babick, F., Ghanem, A., Gaillard, C., Mech, A., Rauscher, H., Weigel, S., Friedrich, C. M. (2017). The NanoDefiner e-tool — A decision support framework for recommendation of suitable measurement techniques for the assessment of potential nanomaterials. 2017 IEEE 12th Nanotechnology Materials and Devices Conference (NMDC). doi:10.1109/nmdc.2017.8350509
Wohlleben, W., Mielke, J., Bianchin, A., Ghanem, A., Freiberger, H., Rauscher, H., Gemeinert, M., & Hodoroaba, V.-D. (2017). Reliable nanomaterial classification of powders using the volume-specific surface area method. Journal of Nanoparticle Research, 19(2). doi:10.1007/s11051-017-3741-x
Babick, F., Mielke, J., Wohlleben, W., Weigel, S., & Hodoroaba, V.-D. (2016). How reliably can a material be classified as a nanomaterial? Available particle-sizing techniques at work. Journal of Nanoparticle Research, 18(6). doi:10.1007/s11051-016-3461-7
Peters, R., Herrera-Rivera, Z., Undas, A., van der Lee, M., Marvin, H., Bouwmeester, H., & Weigel, S. (2015). Single particle ICP-MS combined with a data evaluation tool as a routine technique for the analysis of nanoparticles in complex matrices. Journal of Analytical Atomic Spectrometry, 30(6), 1274–1285. doi:10.1039/c4ja00357h
European Union (2011). Commission Recommendation of 18 October 2011 on the definition of nanomaterial (2011/696/EU). Official Journal of the European Union, L 275, pp. 38–40.
In MDPI Materials Special Issue Nanomaterial Characterization Methods: Leaping Towards Validation:
Brüngel, R., Rückert, J., Wohlleben, W., Babick, F., Ghanem, A., Gaillard, C., Mech, A., Rauscher, H., Hodoroaba, V.-D., Weigel, S., Friedrich, C. M. (2019). NanoDefiner e-Tool: An Implemented Decision Support Framework for Nanomaterial Identification. Materials, 12(19), 3247. doi:10.3390/ma12193247
BibTeX:@article{Bruengel_2019,
doi = {10.3390/ma12193247},
url = {https://www.mdpi.com/1996-1944/12/19/3247/htm},
year = 2019,
month = {oct},
publisher = {{MDPI} {AG}},
journal = {Materials},
volume = {12},
number = {19},
pages = {3247},
author = {Raphael Br\"ungel and Johannes R\"uckert and Wendel Wohlleben and Frank Babick and Antoine Ghanem and Claire Gaillard and Agnieszka Mech and Hubert Rauscher and Vasile-Dan Hodoroaba and Stefan Weigel and Christoph M. Friedrich},
title = {{NanoDefiner e-Tool: An Implemented Decision Support Framework for Nanomaterial Identification}}
}
In Proceedings of the 2017 IEEE 12th Nanotechnology Materials and Devices Conference (NMDC):
Brüngel, R., Rückert, J., Wohlleben, W., Babick, F., Ghanem, A., Gaillard, C., Mech, A., Rauscher, H., Weigel, S., Friedrich, C. M. (2017). The NanoDefiner e-tool — A decision support framework for recommendation of suitable measurement techniques for the assessment of potential nanomaterials. 2017 IEEE 12th Nanotechnology Materials and Devices Conference (NMDC). doi:10.1109/nmdc.2017.8350509
BibTeX:@inproceedings{Bruengel_2017,
doi={10.1109/NMDC.2017.8350509},
url={https://ieeexplore.ieee.org/document/8350509/},
year={2017},
month={oct},
publisher={IEEE},
booktitle={2017 IEEE 12th Nanotechnology Materials and Devices Conference (NMDC)},
pages={71-72},
author={Raphael Br\"ungel and Johannes R\"uckert and Wendel Wohlleben and Frank Babick and Antoine Ghanem and Claire Gaillard and Agnieszka Mech and Hubert Rauscher and Stefan Weigel and Christoph M. Friedrich},
title={{The NanoDefiner e-tool -- A decision support framework for recommendation of suitable measurement techniques for the assessment of potential nanomaterials}}
}